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Product Name | ML-314 |
Description | An NTS1 agonist; selective for NTS1 over NTS2 in a cell-based assay of receptor/β-arrestin complex formation (EC50s = 2 and >80 µM, respectively); inactive in an NTS1 calcium flux assay (EC50 = >80 µM); a positive allosteric modulator that increases binding of radiolabaled neurotensin to NTS1 in a concentration-dependent manner; reduces locomotion in dopamine transporter knockout mice and methamphetamine-exposed mice at 20 and 10-30 mg/kg, respectively; reduces methamphetamine self-administration in rats at 30 mg/kg, |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | ML-314 NTS-1 -2 |
Gene, Accession, CAS # | CAS: 1448895-09-7 |
Catalog # | 19550-25 |
Price | $651.00 |
Order / More Info | ML-314 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |