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Product Name | AS-2863619 |
Description | A dual inhibitor of Cdk8 and Cdk19 (IC50s = 0.6 and 4.3 nM, respectively); induces Foxp3 expression in isolated mouse naive T cells at 1 µM alone or synergistically with TGF-β; decreases ear edema and induces production of Foxp3+ Tregs in mice at 30 mg/kg; reduces disease severity in a mouse model of EAE |
Size | 500 µg |
Concentration | n/a |
Applications | n/a |
Other Names | 2241300-50-3 AS2863619 Cdk 8 19 Foxp-3 + TGFβ auto immune |
Gene, Accession, CAS # | CAS: 2241300-51-4 |
Catalog # | 30976-500 |
Price | $68.00 |
Order / More Info | AS-2863619 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |