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Product Name | GLPG0974 |
Description | A antagonist of FFAR2/GPR43 (IC50 = 9 nM); selective for FFAR2 over FFAR3 at 50s = 27 and 43 nM, respectively), as well as acetate-induced expression of CD11b activation-specific epitope on neutrophils in isolated human whole blood (IC50 = 438 nM); inhibits hFFAR2-DREADD (IC50 = 36.31 nM in a cell-based β-arrestin-2 recruitment assay) inhibits GLP-1 secretion induced by sorbic acid in isolated colonic crypts from mice expressing hFFAR2-DREADD-HA at 10 µM |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | GLPG-0974 FA FFAR-2 3 GPR-43 CD-11b CD11-b hFFAR2DREADD GLP1 |
Gene, Accession, CAS # | CAS: 1391076-61-1 |
Catalog # | 28108-1 |
Price | $62.00 |
Order / More Info | GLPG0974 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |