GLPG0974 from CAYMAN CHEMICAL COMPANY

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Product NameGLPG0974
DescriptionA antagonist of FFAR2/GPR43 (IC50 = 9 nM); selective for FFAR2 over FFAR3 at 50s = 27 and 43 nM, respectively), as well as acetate-induced expression of CD11b activation-specific epitope on neutrophils in isolated human whole blood (IC50 = 438 nM); inhibits hFFAR2-DREADD (IC50 = 36.31 nM in a cell-based β-arrestin-2 recruitment assay) inhibits GLP-1 secretion induced by sorbic acid in isolated colonic crypts from mice expressing hFFAR2-DREADD-HA at 10 µM
Size1 mg
Concentrationn/a
Applicationsn/a
Other NamesGLPG-0974 FA FFAR-2 3 GPR-43 CD-11b CD11-b hFFAR2DREADD GLP1
Gene, Accession, CAS #CAS: 1391076-61-1
Catalog #28108-1
Price$62.00
Order / More InfoGLPG0974 from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
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