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Product Name | PTC-124 |
Description | A nonaminoglycoside that has been reported to selectively induce ribosomes to read through premature nonsense stop signals on mRNA, thus allowing the production of full length, functional proteins (IC50 = 7 nM); 60 mg/kg s.c. injection or 0.3-0.9 mg/ml orally has been shown to restore CFTR protein expression and function in a mouse model of cystic fibrosis caused by nonsense mutations |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Ataluren |
Gene, Accession, CAS # | CAS: 775304-57-9 |
Catalog # | 16758-10 |
Price | $87 |
Order / More Info | PTC-124 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |