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Product Name | [cPP1-7,NPY19-23,Ala31,Aib32,Gln34] - Pancreatic Polypeptide (human) (acetate) |
Description | An agonist of NPY receptor Y5; inhibits forskolin-induced cAMP production in HEK293 cells expressing the Y5 receptor (EC50 = 17 nM); selectively binds to Y5 (IC50 = 0.24 nM in HEK293 cells expressing the human receptor) over Y1, Y2, and Y4 (IC50s = 530, >500, and 51 nM, respectively, in BHK-21 cells expressing the human receptors); increases VEGF levels, as well as endothelial branch length and branch points, in 4T1 cells in a concentration-dependent manner; induces relaxation of vasopressin-precontracted rat mesenteric arteries at 1 µM; increases food intake in rats at 0.2 and 2 nmol/animal, i.c.v. |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 313988-89-5 (Gly1,Ser3·22,Gln4·34,Thr6,Arg19,Tyr21,Ala23·31,Aib32) hPancreatic HEK 293 4t 1 BHK21 Y 2 4 hpp |
Gene, Accession, CAS # | n/a |
Catalog # | 36718-10 |
Price | $542.00 |
Order / More Info | [cPP1-7,NPY19-23,Ala31,Aib32,Gln34] - Pancreatic Polypeptide (human) (acetate) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |