[cPP1-7,NPY19-23,Ala31,Aib32,Gln34] - Pancreatic Polypeptide (human) (acetate) from CAYMAN CHEMICAL COMPANY

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Product Name[cPP1-7,NPY19-23,Ala31,Aib32,Gln34] - Pancreatic Polypeptide (human) (acetate)
DescriptionAn agonist of NPY receptor Y5; inhibits forskolin-induced cAMP production in HEK293 cells expressing the Y5 receptor (EC50 = 17 nM); selectively binds to Y5 (IC50 = 0.24 nM in HEK293 cells expressing the human receptor) over Y1, Y2, and Y4 (IC50s = 530, >500, and 51 nM, respectively, in BHK-21 cells expressing the human receptors); increases VEGF levels, as well as endothelial branch length and branch points, in 4T1 cells in a concentration-dependent manner; induces relaxation of vasopressin-precontracted rat mesenteric arteries at 1 µM; increases food intake in rats at 0.2 and 2 nmol/animal, i.c.v.
Size10 mg
Concentrationn/a
Applicationsn/a
Other Names313988-89-5 (Gly1,Ser3·22,Gln4·34,Thr6,Arg19,Tyr21,Ala23·31,Aib32) hPancreatic HEK 293 4t 1 BHK21 Y 2 4 hpp
Gene, Accession, CAS #n/a
Catalog #36718-10
Price$542.00
Order / More Info[cPP1-7,NPY19-23,Ala31,Aib32,Gln34] - Pancreatic Polypeptide (human) (acetate) from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

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