CS2164 from CAYMAN CHEMICAL COMPANY
Search, find, compare suppliers for CS2164 products.
| Edit | |
|---|---|
| Product Name | CS2164 |
| Description | A multi-kinase inhibitor; inhibits VEGFR1, -2, and -3 (IC50s = 8, 7, and 9 nM, respectively), PDGFRα and PDGFRβ (IC50s = 1 and 93 nM), c-Kit (IC50 = 4 nM), Aurora B kinase (IC50 = 9 nM), and FMS (IC50 = 7 nM); selective for these kinases over a panel of 72 additional kinases, 76 GPCRs, two phosphatases, and nine ion channels (IC50s = >100 nM for all); inhibits VEGF-induced proliferation of HUVECs (GI50 = 20.7 nM) and PDGF-induced proliferation of NIH3T3 cells (GI50 = 44.16 nM); reduces tumor vascularization and tumor growth in a COLO 320 mouse xenograft model at 20 mg/kg; reduces tumor volume in A549, HCT-8, SMMC-7721, and MGC803 mouse xenograft models from 2.5-40 mg/kg |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Chiauranib|Ibcasertib |
| Gene, Accession, CAS # | CAS: 1256349-48-0 |
| Catalog # | 38766-5 |
| Price | $189.00 |
| Order / More Info | CS2164 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY