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Product Name | Dofequidar |
Description | A quinoline derivative and inhibitor of multidrug resistance; inhibits P-glycoprotein in a photolabeling assay at 100 µM; increases intracellular accumulation of [3H]-vincristine in HL-60R cells endogenously expressing the gene encoding MRP at 10 µM; restores susceptibility to vincristine- or doxorubicin-induced cytotoxicity in vincristine-resistant P388, vincristine-resistant K562, and doxorubicin-resistant K562 cells; increases survival in a vincristine-resistant P388 murine leukemia model compared with untreated controls at 80 mg/kg twice per day when administered in combination with vincristine |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | MS-209 MS209 multi-drug glyco-protein HL60R P-388 K-562 |
Gene, Accession, CAS # | CAS: 129716-58-1 |
Catalog # | 30925-1 |
Price | $44.00 |
Order / More Info | Dofequidar from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |