MSA-2 from CAYMAN CHEMICAL COMPANY
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| Product Name | MSA-2 |
| Description | A STING agonist; binds to wild-type and HAQ variant STING in a 3H-cGAMP filtration binding assay (EC50s = 2.48 and 1.72 µM, respectively); induces secretion of IFN-β from THP-1 cells by 129% relative to induction by 2'3'-cGAMP at 30 µM; reduces tumor growth in an MC-38 syngeneic mouse model of colon carcinoma in a dose-dependent manner and induces tumor regression at 450 µg, intratumorally, and 50 mg/kg, s.c.; acts synergistically with an anti-PD-1 antibody in MC-38, CT26, B16/F10, and LL/2 syngeneic mouse models |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 5,6-dimethoxy-γ-oxo-benzo[b]thiophene-2-Butanoic Acid |
| Gene, Accession, CAS # | CAS: 129425-81-6 |
| Catalog # | 30140-1 |
| Price | $32.00 |
| Order / More Info | MSA-2 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY