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Antigenic Specificity | Human CD51/61 |
Clone | 23C6 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | fluorescein (FITC) conjugate |
Size | 25 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | FITC anti-human CD51/61. CD51/CD61 is an integrin complex known as αVβ3. It is expressed at high levels on osteoclasts, endothelial cells, and melanoma cells and at low levels on platelets and macrophages. CD51 is a heterodimer composed of disulfide-linked 125 kD and 24 kD proteins. CD61 is also a member of the integrin family known as gpIIIa or β3 integrin. It is a 110 kD common β subunit of CD51/CD61 or CD41/CD61 complex. CD51/CD61, also known as the vitronectin receptor, mediates the binding of platelets to immobiliz |
Immunogen | n/a |
Other Names | Vitronectin receptor, Integrin αV/β3, ITGAV, ITGB3 |
Gene, Accession # | Gene ID: 3685, 3690 |
Catalog # | 304403 |
Price | $83 |
Order / More Info | Human CD51/61 Antibody from BIOLEGEND |
Product Specific References | PubMed: 23345412 |