Human CD220 Antibody from BIOLEGEND

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Antigenic SpecificityHuman CD220
CloneB6.220
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b, κ
Formatpurified
Size100 µg
Concentrationn/a
ApplicationsFlow Cytometry (FC)
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DescriptionPurified anti-human CD220. CD220, also known as insulin receptor, is a type I transmembrane receptor tyrosine kinase composed of two extracellular α-subunits and two transmembrane β-subunits. Binding insulin, the insulin receptor forms a heterotetramer of two units to induce autophosphorylation and activation of the tyrosine kinase activity of the receptor. Activation of insulin receptor leads to subsequent downstream signaling in metabolic regulation, inducing glucose uptake, cell growth, differentiation, and apoptosis.
ImmunogenHuman insulin receptor/freund?s adjuvant
Other NamesInsulin Receptor
Gene, Accession #Gene ID: 3643
Catalog #352602
Price$136
Order / More InfoHuman CD220 Antibody from BIOLEGEND
Product Specific ReferencesPubMed: 30343902, 30343902
BIOLEGEND
BIOLEGEND
BIOLEGEND
8999 BioLegend Way
San Diego CA 92121
P: (858) 455-9588
P: 1-877-Bio-Legend (246-5343)
F: (858) 455-9587

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