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Antigenic Specificity | Human CD158b/j (KIR2DL2/L3/S2) |
Clone | DX27 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, κ |
Format | allophycocyanin (APC) conjugate |
Size | 25 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | APC anti-human CD158b/j (KIR2DL2/L3/S2). CD158b is expressed on natural killer cells and a subset of T cells. It is a member of the immunoglobulin superfamily containing two immunoglobulin C2-type domains. Both variants and alternative isoforms of CD158b have been reported. The interaction of CD158b with specific HLA-C antigens on a target cell (HLA-Cw1, HLA-Cw3, HLA-Cw7 alleles, for example) inhibits cytotoxicity and prevents target cell lysis and death. The interactions between KIR and MHC class I are thought to be important in NK ce |
Immunogen | n/a |
Other Names | CD158b1 (KIR2DL2, p58.2), CD158b2 (KIR2DL3, p58.3), CD158j (KIR2DS2, p50.2), KIR-NKAT2 |
Gene, Accession # | Gene ID: 3803 |
Catalog # | 312611 |
Price | $142 |
Order / More Info | Human CD158b/j (KIR2DL2/L3/S2) Antibody from BIOLEGEND |
Product Specific References | PubMed: 25122796, 27930745, 29854709 |