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Antigenic Specificity | CCL4 |
Clone | W15138A |
Host Species | Rat |
Reactive Species | human |
Isotype | IgG2a, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-CCL4. CCL4 is an important proinflammatory cytokine involved in acute and chronic inflammatory responses. CCL4 attracts monocytes, natural killer (NK) cells, dendritic cells (DCs), and lymphocytes to sites of injury and inflammation. CCL4 signals through G-protein-coupled receptor CCR5. Because CCR5 is a major co-receptor for M-tropic HIV strains, the anti-HIV effects of CCL4 have been explored. Thus, the binding of CCL4 to CCR5 inhibits HIV entry and reduces the cell surface expression of CCR5. CCL4 |
Immunogen | Partial human CCL4 recombinant protein (24-92 a.a.) expressed in E. coli. |
Other Names | C-C motif chemokine 4, immune activation protein 2 (ACT-2), Macrophage inflammatory protein 1-beta, MIP-1beta, Protein H400, SIS-gamma, Small inducible cytokine A4 |
Gene, Accession # | Gene ID: 6351 |
Catalog # | 686202 |
Price | $288 |
Order / More Info | CCL4 Antibody from BIOLEGEND |
Product Specific References | n/a |