Granzyme B Antibody from BIOLEGEND

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Antigenic SpecificityGranzyme B
CloneO94E6/GZMB
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2a, κ
Formatpurified
Size25 µg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionPurified anti-Granzyme B. Granzyme B is a serine protease that is produced mainly by cytotoxic T cells (CTL) and natural killer (NK) cells. It plays an important role in cytotoxic lymphocyte-mediated apoptosis, chronic inflammation, and impaired wound healing. Granzyme B is packaged in cytoplasmic granules that are exocytosed towards a bound target cell, which subsequently activates multiple protein substrates that induce apoptosis. Perforin facilitates the transfer of Granzyme B into the target cell. Most circulating CD
ImmunogenRecombinant fragment corresponding to amino acids 21-247 of Human Granzyme B produced in E. coli.
Other NamesGranzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1, GZMB, CCP1, Asp-ase, CSPB, CTLA-1, CGL-1, CGL1
Gene, Accession #Gene ID: 3002
Catalog #674301
Price$101
Order / More InfoGranzyme B Antibody from BIOLEGEND
Product Specific Referencesn/a
BIOLEGEND
BIOLEGEND
BIOLEGEND
8999 BioLegend Way
San Diego CA 92121
P: (858) 455-9588
P: 1-877-Bio-Legend (246-5343)
F: (858) 455-9587

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http://www.biolegend.com

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