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Antigenic Specificity | Mouse CD121a (IL-1 R, Type I/p80) |
Clone | JAMA-147 |
Host Species | Armenian Hamster |
Reactive Species | mouse |
Isotype | IgG |
Format | purified |
Size | 500 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC), IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-mouse CD121a (IL-1 R, Type I/p80). CD121a is an 80 kD IL-1 receptor type I. It is a transmembrane glycoprotein and a member of the immunoglobulin superfamily expressed on T cells, thymocytes, dendritic cells, fibroblasts, vascular endothelial cells, epithelial cells and neural cells. CD121a binds the mature forms of IL-1α, IL-1β, and IL-1Ra proteins. High affinity binding and signaling by the type I IL-1 receptor requires CD121a and the accessory protein, IL-1R AcP, which does not bind IL-1 alone, but forms a dimer capable of bin |
Immunogen | Extracellular domain of mouse IL-1R1 |
Other Names | IL-1 Receptor type I, IL-1RI, p80 |
Gene, Accession # | Gene ID: 16177 |
Catalog # | 113502 |
Price | $258 |
Order / More Info | Mouse CD121a (IL-1 R, Type I/p80) Antibody from BIOLEGEND |
Product Specific References | PubMed: 22615129 |