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Antigenic Specificity | Human CD32B/C |
Clone | 4F5/CD32 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | phycoerythrin (PE) conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PE anti-human CD32B/C. CD32B (FCGR2B) and CD32C (FCGR2C) are 40 kDa, type I transmembrane proteins that are members of the Ig superfamily of low-affinity immunoglobulin gamma Fc receptors. CD32B has a cytoplasmic tail that contains an immunoreceptor tyrosine-based inhibition motif (ITIM), while CD32C contains an immunoreceptor tyrosine-based activation motif (ITAM). CD32B and CD32C are low affinity receptor for monomeric IgG but also bind IgG complexes. CD32B and CD32C are expressed on B cells, subsets of monocytes,macrophages and granulocytes, platelets, mast cells, and is a negative regulator of cell activation, proliferation, endocytosis, phagocytosis, and degranulation. |
Immunogen | Extracellular domain of human CD32B |
Other Names | FCGR2B, FCgRIIB, FCGR2C, FCRIIC, IGFR2 |
Gene, Accession # | Gene ID: 2213, 9103 |
Catalog # | 398404 |
Price | $335 |
Order / More Info | Human CD32B/C Antibody from BIOLEGEND |
Product Specific References | n/a |