Edit |   |
---|---|
Antigenic Specificity | Human CD117 (c-kit) |
Clone | 104D2 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | allophycocyanin (APC) conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | APC anti-human CD117 (c-kit). CD117 is a 145 kD protein tyrosine kinase also known as c-Kit. It is a receptor for stem cell factor or c-Kit ligand. CD117 is expressed on pluripotent hematopoietic progenitor cells (approximately 1-4% bone marrow cells), mast cells, and acute myeloid leukemia cells (AML). CD117 binding of c-Kit ligand induces phosphorylation of CD117 and stimulates proliferation and survival of primitive hematopoietic stem cells as well as erythroid-committed and granulo-monocytic committed cells. |
Immunogen | MOLM-1 megakaryocytic cell line |
Other Names | Stem cell factor receptor, c-kit, mast cell growth factor receptor, steel factor receptor |
Gene, Accession # | Gene ID: 3815 |
Catalog # | 313206 |
Price | $288 |
Order / More Info | Human CD117 (c-kit) Antibody from BIOLEGEND |
Product Specific References | PubMed: 21674817, 23718190, 25369328, 27432971, 30872578, 29162563, 30920150, 29882687, 30503706, 32180719, 31437490, 33264627, 33513358, 33741501 |