Human CD170 (Siglec-5) Antibody from BIOLEGEND
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| Antigenic Specificity | Human CD170 (Siglec-5) |
| Clone | 1A5 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1, κ |
| Format | allophycocyanin (APC) conjugate |
| Size | 25 tests |
| Concentration | n/a |
| Applications | Flow Cytometry (FC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | APC anti-human CD170 (Siglec-5). CD170, also known as Siglec-5, is a single pass transmembrane protein member of the immunoglobulin superfamily. On the cell surface, CD170 forms a 140 kD dimer. The cytoplasmic domain of Siglec-5 contains two ITIM motifs that recruit the tyrosine-phosphatases SHP-1 and SHP-2 after tyrosine-phosphorylation, which in turn results in the inhibition of cell signaling. Siglec-5 is expressed by granulocytes, monocytes/macrophages, subsets of lymphocytes, and a subset of activated dendritic cells. Sigl |
| Immunogen | Extracellular region of Siglec-5 |
| Other Names | OBBP2, CD33L2, OB-BP2 |
| Gene, Accession # | Gene ID: 8778 |
| Catalog # | 352005 |
| Price | $149 |
| Order / More Info | Human CD170 (Siglec-5) Antibody from BIOLEGEND |
| Product Specific References | n/a |
BIOLEGEND
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