Description | Pacific Blue™ anti-mouse CD3. CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex |
Product Specific References | PubMed: 19234143, 19074554, 21357532, 22396593, 24442435, 24760891, 24951817, 25086170, 25024368, 23851361, 26833183, 28542148, 28696253, 28696253, 28542148, 29127360, 29723263, 29768180, 28801233, 30575523, 30673616, 30747722, 30995478, 31056957, 31227691, 29887374, 30635393, 29887373, 30995478, 30799288, 29768180, 29463868, 29868034, 31073070, 31163619, 31237933, 32773038, 32313567, 33053342, 32737655, 33053342, 33171124, 33761361 |