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Antigenic Specificity | Mouse Ly49H |
Clone | 3D10 |
Host Species | Mouse |
Reactive Species | mouse |
Isotype | IgG1, κ |
Format | TotalSeq™-B oligomer conjugate |
Size | 10 µg |
Concentration | n/a |
Applications | PG |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TotalSeq™-B0839 anti-mouse Ly49H. Ly49H, also known as Cmv1 and Klra8, is a 28.3 kD protein. It is expressed on NK cells (but not on NKT cells) from C57BL/6 mice (but not Balb/c or DBA/2 mice). Expression of Ly49H has been associated with resistance to MCMV infection in C57BL/6 mice. Modulation of Ly49H expression by its antibody made MCMV-resistant C57BL/6 mice susceptible to infection. Unlike Ly49A, Ly49H lacks the ITIM (immunoreceptor tyrosine-based inhibitory motif) but has ITAM (immunoreceptor tyrosine-based activation |
Immunogen | C1498-Ly49A/H transfectant |
Other Names | Klra8, Cmv1 |
Gene, Accession # | Gene ID: 16639 |
Catalog # | 144721 |
Price | $369 |
Order / More Info | Mouse Ly49H Antibody from BIOLEGEND |
Product Specific References | n/a |