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Antigenic Specificity | Chk1 |
Clone | P82G1D5 |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1, κ |
Format | purified |
Size | 25 µg |
Concentration | n/a |
Applications | Western Blot (WB), ICC, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-Chk1. Checkpoint kinase 1, or Chk1, is a protein serine/threonine kinase that is an essential component of the ATR pathway, which links DNA abnormalities and double strand breaks to downstream signaling events. It is activated through phosphorylation by ATR at serine residues 345 and 317. Once activated, Chk1 phosphorylates downstream effectors of S, G2, and M phases of the cell cycle to induce transcription regulation, energy consumption alterations, cell cycle arrest, and DNA repair. In cells chall |
Immunogen | Partial recombinant human Chk1 protein |
Other Names | Chek1, Checkpoint Kinase 1, EC 2.7.11.1, Checkpoint, S. Pombe. Homolog Of, 1, Chk1-S |
Gene, Accession # | Gene ID: 1111 |
Catalog # | 940101 |
Price | $118 |
Order / More Info | Chk1 Antibody from BIOLEGEND |
Product Specific References | n/a |