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Antigenic Specificity | Wnt3A |
Clone | BL28556 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b, κ |
Format | purified |
Size | 25 µg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-Wnt3A. Wnt3a, one of Wnt family members, plays a key role in carcinogenesis. Studies have shown that Wnt3a can both promote and suppress cancer progression depending on the cancer type. Mechanistically, Wnt3a activates downstream signaling pathways in a canonical manner by binding to its receptor Frizzled (Fz) and co-receptor lipoprotein receptor-related proteins 5/6 (LRP5/6), which ultimately promote nuclear translocation of the transcription factor b-catenin. Wnt3A is also involved in non-oncogenic p |
Immunogen | n/a |
Other Names | Protein Wnt-3a |
Gene, Accession # | Gene ID: 89780 |
Catalog # | 855601 |
Price | $106 |
Order / More Info | Wnt3A Antibody from BIOLEGEND |
Product Specific References | n/a |