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Antigenic Specificity | Mouse TNF-α |
Clone | MP6-XT22 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG1, κ |
Format | Brilliant Violet 421™ conjugate |
Size | 50 µg |
Concentration | n/a |
Applications | Intracellular Staining for Flow Cytometry (ICFC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Brilliant Violet 421™ anti-mouse TNF-α. TNF-α is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells. Many transformed cell lines also secrete TNF-α. Monomeric mouse TNF-α is a 156 amino acid protein (N-glycosylated) with a reported molecular weight of 17.5 kD. TNF-α forms multimeric complexes; stable trimers are most common in solution. A 26 kD membrane form of TNF-α has also been described. TNF-α binding to surface receptors elicits a wide array of biologic activities including: cytolysis and cytostasis of many tu |
Immunogen | E. coli-expressed, recombinant mouse TNF-α |
Other Names | Tumor necrosis factor-α, Cachectin, Necrosin, Macrophage cytotoxic factor (MCF), Differentiation inducing factor (DIF), TNFSF-2, TNF-a, TNF-alpha |
Gene, Accession # | Gene ID: 21926 |
Catalog # | 506328 |
Price | $242 |
Order / More Info | Mouse TNF-α Antibody from BIOLEGEND |
Product Specific References | PubMed: 27818384, 28666759, 28666759, 30314757, 30952606, 31606264, 30709740, 30314757, 30314757, 30709740, 30712873, 32380006, 32640259, 33171124, 33212014, 33521747, 33515487, 33636129, 33979612 |