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Antigenic Specificity | Human CD273 (B7-DC, PD-L2) |
Clone | A20050B |
Host Species | Rat |
Reactive Species | human |
Isotype | IgG2b, κ |
Format | purified, low endotoxin, azide-free |
Size | 1 mg |
Concentration | n/a |
Applications | Block |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Ultra-LEAF™ Purified anti-human CD273 (B7-DC, PD-L2). PD-L2 is a type I transmembrane protein of 273 amino acids, and it is a member of the B7 family. Human PD-L2 has 70% amino acid identity to its mouse orthologue. PD-L2 is the second ligand for PD-1, and its binding to PD-1 leads to the inhibition of T cell receptor-mediated lymphocyte proliferation and cytokine secretion. PD-L2/PD-1 interaction suppresses immune responses against autoantigens and tumors and plays an important role in the maintenance of peripheral immune tolerance. Antibody block |
Immunogen | Recombinant human PD-L2 (B7-DC, CD273)-Fc chimera |
Other Names | CD273, Programmed cell death 1 ligand 2 (PD-L2), B7 dendritic cell molecule (B7-DC), Butyrophilin B7-DC, PDCD1 Ligand 2 |
Gene, Accession # | Gene ID: 80380 |
Catalog # | 947804 |
Price | $765 |
Order / More Info | Human CD273 (B7-DC, PD-L2) Antibody from BIOLEGEND |
Product Specific References | n/a |