Edit |   |
---|---|
Antigenic Specificity | Mouse CD276 (B7-H3) |
Clone | RTAA15 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a, κ |
Format | phycoerythrin (PE) conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PE anti-mouse CD276 (B7-H3). B7-H3 is a member of the B7 gene family. It has 88% amino acid sequence identity with human B7-H3. It is mostly expressed on professional APCs, including B cells, macrophages, and dendritic cells. Its expression on dendritic cells appears to be up-regulated by LPS. B7-H3 protein inhibits T cell activation and cytokine production. It was reported that monoclonal antibody against B7-H3 enhanced T cell proliferation in vitro and led to exacerbated EAE in vivo. Therefore, B7-H3 may be a negative reg |
Immunogen | n/a |
Other Names | B7H3, B7RP-2 |
Gene, Accession # | Gene ID: 102657 |
Catalog # | 124508 |
Price | $275 |
Order / More Info | Mouse CD276 (B7-H3) Antibody from BIOLEGEND |
Product Specific References | PubMed: 22311925, 30992475, 31291568, 31771985 |