Description | Alexa Fluor® 488 anti-mouse CD3. CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex |
Product Specific References | PubMed: 17606630, 23180724, 24743435, 24295829, 25172501, 25124037, 25858253, 26019294, 28498310, 29084966, 28498310, 29176738, 30057172, 27736323, 30741527, 31409799, 30869653, 29887373, 31475002, 31053504, 30889381, 31097342, 30057172, 28350989, 30057172, 31831780, 32195350, 29315518, 31427644, 30462731, 32555459, 33298977, 32955487, 33500260, 33945793, 34157301 |