PTEN Antibody from BIOLEGEND

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Antigenic SpecificityPTEN
CloneW20041H
Host SpeciesRat
Reactive Specieshuman
IsotypeIgG2b, κ
Formatpurified
Size25 µg
Concentrationn/a
ApplicationsIntracellular Staining for Flow Cytometry (ICFC)
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DescriptionPurified anti-PTEN. PTEN was discovered as a tumor suppressor with lipid and protein phosphatase activity. Heterozygous loss of PTEN in mice contribute to the development of a variety of types of cancer, suggesting that insufficient PTEN activity results in increased cancer susceptibility. PTEN negatively regulates the PI3K/AKT pathway by dephosphorylating the second messenger phosphoinositide 3,4,5-triphosphate (PIP3) produced by phosphoinositide 3-kinase (PI3K), which results in inhibition of abnormal cell prolif
ImmunogenPartial recombinant human PTEN protein
Other NamesBZS, TEP1, PTEN1, PTENbeta, Phosphatase and tensin homolog, MMAC1, CWS1, DEC, GLM2, MHAM
Gene, Accession #Gene ID: 5728
Catalog #366201
Price$147
Order / More InfoPTEN Antibody from BIOLEGEND
Product Specific Referencesn/a
BIOLEGEND
BIOLEGEND
BIOLEGEND
8999 BioLegend Way
San Diego CA 92121
P: (858) 455-9588
P: 1-877-Bio-Legend (246-5343)
F: (858) 455-9587

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