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Antigenic Specificity | Mouse/Human Siglec-15 |
Clone | MK4.5 |
Host Species | Mouse |
Reactive Species | mouse, human |
Isotype | IgG1, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC), Intracellular Staining for Flow Cytometry (ICFC), ICC, ELISA Capture, Direct ELISA |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-mouse/human Siglec-15. Siglec-15, also known as Siglec-I and CD33L3, is a member of the Sialic acid-binding Ig-like lectin family and is a type I single pass transmembrane protein. Siglec-15 is expressed by a subset of myeloid cells, osteoclasts, and can be upregulated by certain cancers. Siglec-15 plays an important role in osteoclastogenesis and bone remodeling during normal development and in bone absorption in arthritis. Furthermore, Siglec-15 suppresses antigen-specific T cell responses and is therefore considere |
Immunogen | Mouse Siglec-15-huIgG Fc fusion protein |
Other Names | Sialic acid-binding Ig-like lectin 15, CD33 antigen-like 3 |
Gene, Accession # | Gene ID: 620235, 284266 |
Catalog # | 164602 |
Price | $276 |
Order / More Info | Mouse/Human Siglec-15 Antibody from BIOLEGEND |
Product Specific References | n/a |