Edit |   |
---|---|
Antigenic Specificity | Mouse TNF-α |
Clone | MP6-XT22 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG1, κ |
Format | biotin conjugate |
Size | 50 µg |
Concentration | n/a |
Applications | ELISA Detection, ELISPOT Detection, Intracellular Staining for Flow Cytometry (ICFC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Biotin anti-mouse TNF-α. TNF-α is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells. Many transformed cell lines also secrete TNF-α. Monomeric mouse TNF-α is a 156 amino acid protein (N-glycosylated) with a reported molecular weight of 17.5 kD. TNF-α forms multimeric complexes; stable trimers are most common in solution. A 26 kD membrane form of TNF-α has also been described. TNF-α binding to surface receptors elicits a wide array of biologic activities including: cytolysis and cytostasis of many tu |
Immunogen | E. coli-expressed, recombinant mouse TNF-α |
Other Names | Tumor necrosis factor-α, Cachectin, Necrosin, Macrophage cytotoxic factor (MCF), Differentiation inducing factor (DIF), TNFSF-2, TNF-a, TNF-alpha |
Gene, Accession # | Gene ID: 21926 |
Catalog # | 506311 |
Price | $101 |
Order / More Info | Mouse TNF-α Antibody from BIOLEGEND |
Product Specific References | PubMed: 19684159, 25980007, 26555441, 31848486 |