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Antigenic Specificity | Mouse LAP (TGF-β1) |
Clone | TW7-20B9 |
Host Species | Mouse |
Reactive Species | mouse |
Isotype | IgG1, κ |
Format | purified, low endotoxin, azide-free |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC), IP, Neut, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Ultra-LEAF™ Purified anti-mouse LAP (TGF-β1). Transforming growth factor beta (TGF-β) is a cytokine that has critical functions in immune response by regulating Treg and Th17 cells. TGF-β is first synthesized as pro-TGF-β and then it is cleaved by furin proprotein convertase in the Golgi apparatus to produce the dimeric propeptides called latency-associated peptide (LAP) that non-covalently associates with the dimeric mature TGF-β to prevent its activity. This complex can further associate with latent-TGF-β-binding protein (LTBP) to produce |
Immunogen | Mouse Tgfb1-transduced P3U1 cells |
Other Names | Transforming growth factor-beta 1 (TGF-b1), Latency Associated Peptide (LAP), TGFB1, DPD1 |
Gene, Accession # | Gene ID: 21803 |
Catalog # | 141307 |
Price | $270 |
Order / More Info | Mouse LAP (TGF-β1) Antibody from BIOLEGEND |
Product Specific References | n/a |