Cytokeratin 14 / CK14 / KRT14 Antibody from BIORBYT LTD.

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Antigenic SpecificityCytokeratin 14 / CK14 / KRT14
CloneKRT14/532
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG3, kappa
FormatProtein G purified
Size100 ug, 20 ug
Concentrationn/a
ApplicationsIHC-P
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DescriptionCytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore, this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics, and in identifying metaplastic carcinomas of the breast.
ImmunogenRecombinant full-length human KRT14 protein was used as the immunogen for the Keratin 14 antibody.
Other Namesn/a
Gene, Accession #UniProt: P02533
Catalog #orb749633
Price$764
Order / More InfoCytokeratin 14 / CK14 / KRT14 Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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