S100A8 Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-S100A8 antibody, protein, ELISA kits.
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| Antigenic Specificity | S100A8 |
| Clone | SA6279 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1, kappa |
| Format | Protein G purified |
| Size | 100 ug, 25 ug |
| Concentration | n/a |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The S100 family of proteins are found in vertebrates and are characterized by two calcium-binding sites that have a helix-loop-helix conformation. The family of 24 is divided into three subgroups based on function: those with intracellular, intracellular plus extracellular, and extracellular regulatory effects. The calcium-binding protein S100A8, also called MRP8 or Myeloid-related protein 8, and Calgranulin A, forms a heterodimer with S100A9, called Calprotectin. The heterodimer is expressed by granulocytes, monocytes, and early differentiation states of macrophages, and is known to be an important pro-inflammatory mediator in acute and chronic inflammation. S100A8 and 9 are DAMPs, or Damage-associated molecular pattern molecules, and are able to activate receptors of the innate immune system, one being TLR4. |
| Immunogen | A recombinant protein fragment from the N-terminal region of human S100A8 was used as the immunogen for this antibody. |
| Other Names | n/a |
| Gene, Accession # | Gene ID: 6279 |
| Catalog # | orb749296 |
| Price | $643 |
| Order / More Info | S100A8 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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