PLAUR Antibody from BIORBYT LTD.
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| Edit | |
|---|---|
| Antigenic Specificity | PLAUR |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | unconjugated |
| Size | 50 ul, 100 ul, 200 ul |
| Concentration | n/a |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit polyclonal antibody to PLAUR. Urokinase plasminogen activator surface receptor (uPAR, also known as PLAUR or CD87) is a 4565 kDa, highly glycosylated, GPIanchored membrane protein. It contains three homologous domains (D1D3) of which the Nterminal one (D1) represents the uPAbinding domain. After binding to uPAR, urokinase plasminogen activator (uPA) cleaves plasminogen, generating the active protease plasmin which is involved in a wide variety of physiologic and pathologic processes. In addition to regulating proteolysis, uPAR has important function in cell adhesion, migration and proliferation. Studies reveal that uPAR expression is elevated during inflammation and tissue remodelling and in many human cancers, in which it frequently indicates poor prognosis. |
| Immunogen | Recombinant fusion protein of human PLAUR(NP_002650.1). |
| Other Names | D87, UPAR, URKR |
| Gene, Accession # | UniProt: Q03405 |
| Catalog # | orb154129 |
| Price | $231 |
| Order / More Info | PLAUR Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
BIORBYT LTD.
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P: +44 (0)1223 859 353
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info@biorbyt.com
http://www.biorbyt.com
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Email: info@biorbyt.com
Phone: +1 (415) 906-5211
Fax: +1 (415) 651-8558
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