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Antigenic Specificity | CD27 |
Clone | CDLA27-1R |
Host Species | Recombinant Rabbit |
Reactive Species | human |
Isotype | IgG, kappa |
Format | Protein A purified |
Size | 20 ug, 100 ug |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. CD27 transduces signals that lead to the activation of NF-kB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [Wiki] |
Immunogen | Human CD27 protein was used as the immunogen for the recombinant CD27 antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P26842 |
Catalog # | orb533982 |
Price | $405 |
Order / More Info | CD27 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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