STAT3 Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-STAT3 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | STAT3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 100 ul |
| Concentration | 100 µg/ml BSA |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit polyclonal to STAT3. Signal transducer and activator of transcription 3 (STAT3) is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo-or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT3 is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. STAT3 mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of STAT3. PIAS3 protein is a specific inhibitor of STAT3. Three alternatively spliced transcript variants encoding distinct isoforms have been described. |
| Immunogen | C-terminal region of human STAT3 |
| Other Names | Signal transducer and activator of transcription 3, Acute-phase response factor, APRF |
| Gene, Accession # | UniProt: P40763 |
| Catalog # | orb131830 |
| Price | $527 |
| Order / More Info | STAT3 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
BIORBYT LTD.
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