SNAI1 Antibody from BIORBYT LTD.
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| Antigenic Specificity | SNAI1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | unconjugated |
| Size | 100 ul |
| Concentration | n/a |
| Applications | ELISA, ICC, IHC, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Snail is a zinc-finger transcription factor that can repress E-cadherin transcription. Downregulation of E-cadherin is associated with epithelial-mesenchymal transition during embryonic development, a process also exploited by invasive cancer cells . Indeed, loss of E-cadherin expression is correlated with the invasive properties of some tumors and there is a considerable inverse correlation between Snail and E-cadherin mRNA levels in epithelial tumor cell lines . In addition, Snail blocks the cell cycle and confers resistance to cell death . Phosphorylation of Snail by GSK-3 and PAK1 regulates its stability, cellular localization and function .Tissue specificity: Expressed in a variety of tissues with the highest expression in kidney. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SNAI1. AA range:215-264 |
| Other Names | SNAH; Zinc finger protein SNAI1; Protein snail homolog 1; Protein sna |
| Gene, Accession # | Gene ID: 6615, UniProt: O95863 |
| Catalog # | orb1729726 |
| Price | $296 |
| Order / More Info | SNAI1 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
BIORBYT LTD.
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