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Antigenic Specificity | Pan Cytokeratin Cocktail (Acidic + Basic) |
Clone | AE1 + AE3 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1, kappa |
Format | Protein G purified |
Size | 100 ug, 20 ug |
Concentration | n/a |
Applications | FACS, IF, IHC, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This pan keratin antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which include CK1, CK3-6, CK8, CK10, CK14-16, and CK19. Many studies have shown the usefulness of keratin markers in cancer research and tumor diagnosis. The AE1 + AE3 antibody cocktail is a broad spectrum pan cytokeratin antibody cocktail which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It has been used to characterize the source of various neoplasms and to study the distribution of keratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. It stains cytokeratin present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas. |
Immunogen | Human epidermal keratin was used as the immunogen for this pan Cytokeratin antibody. |
Other Names | n/a |
Gene, Accession # | Gene ID: 3848, 8, 3856, 1, 3853, 5, 3, 3858, 4, 3866, 3880, 6, 3868, 3850, 3851, 14, 10, 3852, 19, 16, 3861, 15 |
Catalog # | orb639459 |
Price | $764 |
Order / More Info | Pan Cytokeratin Cocktail (Acidic + Basic) Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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