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Antigenic Specificity | DMAP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 100 ul |
Concentration | n/a |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit polyclonal to DMAP1.DNA methyltransferase 1-associated protein 1 (DMAP1) is a subunit of several distinct complexesinvolved in the repression or activation of transcription. DMAP1 can independently represstranscription and is targeted to replication foci throughout S phase by interacting directly with the Nterminusof DNA methyltransferase 1 (DNMT1). During late S phase, histone deacetylase 2 (HDAC2)is added to this complex, providing a means to deacetylate histones in transcriptionally inactiveheterochromatin following replication. DMAP1 is also a component of the nucleosomeacetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibilitygene 101 and the pro-apoptotic death-associated protein 6, among others. |
Immunogen | C-terminal region of human DMAP1 |
Other Names | DMAP1,DNA methyltransferase 1associated protein 1,DNMAP1,DNMT1associated protein 1,KIAA1425 |
Gene, Accession # | UniProt: Q9NPF5 |
Catalog # | orb67071 |
Price | $527 |
Order / More Info | DMAP1 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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