CD207 Antibody from BIORBYT LTD.
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| Antigenic Specificity | CD207 |
| Clone | 2G3 |
| Host Species | n/a |
| Reactive Species | human, primate |
| Isotype | IgG1 lambda |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | 1 mg/ml |
| Applications | ELISA, FC, ICC, IHC-Fr |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD207 is a 40 kDa type II transmembrane glycoprotein of the C-type lectin family. It binds to mannose-bearing glycoproteins and glycolipids of microbial and viral antigens, including HIV gp120. CD207 is expressed only in Langerhans cells, which are immature dendritic cells of the epidermis and mucosa, and its expression decreases during Langerhans cells maturation. Upon antigen binding CD207 localizes to the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed membranes, which leads to a nonclassical antigen-processing pathway. |
| Immunogen | Fusion protein of human CD207 extracellular part and IgG Fc fragment |
| Other Names | CLEC4K, langerin |
| Gene, Accession # | Gene ID: 50489, UniProt: Q9UJ71 |
| Catalog # | orb1806417 |
| Price | $304 |
| Order / More Info | CD207 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
BIORBYT LTD.
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Swann Road
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P: +44 (0)1223 859 353
F: +44(0)1223 280 240
info@biorbyt.com
http://www.biorbyt.com
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Biorbyt LLC
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Email: info@biorbyt.com
Phone: +1 (415) 906-5211
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