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Antigenic Specificity | Als2Cr2 / STRADB |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Protein A purified |
Size | 100 ug, 25 ug |
Concentration | n/a |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Als2Cr2, also called STE20-related kinase adapter protein beta (STRAD beta) and ILPIP, is a serine/threonine protein kinase encoded by the STRADB gene, discovered as an XIAP interacting protein. It is a mediator of the XIAP/TAK1 activation of the JNK1 pathway, an apoptosis inhibition mechanism independent of XIAP inhibition of caspases. Alone, it only moderately activates JNKs, but its interaction with XIAP/TAK1 induces a much stronger activation of JNK1, protecting against Caspase 1- or Fas-induced apoptosis. |
Immunogen | A recombinant protein fragment from the interior region of human Als2Cr2 was used as the immunogen for this antibody. |
Other Names | n/a |
Gene, Accession # | Gene ID: 55437 |
Catalog # | orb248114 |
Price | $643 |
Order / More Info | Als2Cr2 / STRADB Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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