Als2Cr2 / STRADB Antibody from BIORBYT LTD.

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Antigenic SpecificityAls2Cr2 / STRADB
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
FormatProtein A purified
Size100 ug, 25 ug
Concentrationn/a
ApplicationsWB
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DescriptionAls2Cr2, also called STE20-related kinase adapter protein beta (STRAD beta) and ILPIP, is a serine/threonine protein kinase encoded by the STRADB gene, discovered as an XIAP interacting protein. It is a mediator of the XIAP/TAK1 activation of the JNK1 pathway, an apoptosis inhibition mechanism independent of XIAP inhibition of caspases. Alone, it only moderately activates JNKs, but its interaction with XIAP/TAK1 induces a much stronger activation of JNK1, protecting against Caspase 1- or Fas-induced apoptosis.
ImmunogenA recombinant protein fragment from the interior region of human Als2Cr2 was used as the immunogen for this antibody.
Other Namesn/a
Gene, Accession #Gene ID: 55437
Catalog #orb248114
Price$643
Order / More InfoAls2Cr2 / STRADB Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

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