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Antigenic Specificity | FADD |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | IgG |
Format | unconjugated |
Size | 100 ul |
Concentration | 1mg/ml |
Applications | IP, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. |
Immunogen | A synthetic peptide of human FADD |
Other Names | FADD; MORT1; GIG3; Protein FADD; FAS-associated death domain protein; FAS-associating death domain-containing protein; Growth-inhibiting gene 3 protein; Mediator of receptor induced toxicity |
Gene, Accession # | Gene ID: 8772, UniProt: Q13158 |
Catalog # | orb1731989 |
Price | $345 |
Order / More Info | FADD Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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