KRT10 / Cytokeratin 10 Antibody from BIORBYT LTD.

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Antigenic SpecificityKRT10 / Cytokeratin 10
CloneKRT10/844
Host SpeciesMouse
Reactive Specieshuman, mouse
IsotypeIgG1, kappa
FormatProtein G purified
Size100 ug, 20 ug
Concentrationn/a
ApplicationsIHC-P, WB
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DescriptionThis mAb recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.
ImmunogenRecombinant human KRT10 protein was used as the immunogen for the Keratin 10 antibody.
Other Namesn/a
Gene, Accession #UniProt: P13645
Catalog #orb749632
Price$764
Order / More InfoKRT10 / Cytokeratin 10 Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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