Factor VIII Antibody from BIORBYT LTD.

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Antigenic SpecificityFactor VIII
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatunconjugated
Size100 ul
Concentrationn/a
ApplicationsELISA, IHC, WB
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DescriptionF8: coagulation factor VIII, procoagulant component. This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.
ImmunogenSynthesized peptide derived from the C-terminal region of human Factor VIII. at AA rangle: 2130-2210
Other NamesF8; F8C; Coagulation factor VIII; Antihemophilic factor; AHF; Procoagulant component
Gene, Accession #Gene ID: 2157, UniProt: P00451
Catalog #orb1730145
Price$296
Order / More InfoFactor VIII Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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