Cullin 5 Antibody from BIORBYT LTD.

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Antigenic SpecificityCullin 5
Clonemonoclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
IsotypeIgG
Formatunconjugated
Size100 ul
Concentration1mg/ml
ApplicationsWB
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DescriptionCore component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor.
ImmunogenRecombinant protein of human Cullin 5
Other NamesCUL-5; VACM1; VACM-1
Gene, Accession #Gene ID: 8065, UniProt: Q93034
Catalog #orb1732099
Price$345
Order / More InfoCullin 5 Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

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