PD-1 Antibody from BIORBYT LTD.
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| Edit | |
|---|---|
| Antigenic Specificity | PD-1 |
| Clone | 5C4.B8 (Nivolumab) |
| Host Species | Human |
| Reactive Species | human, monkey |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.2 mg |
| Concentration | 1 mg/ml |
| Applications | Blocking, FC, IHC, SBR |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PD-1 Antibody |
| Immunogen | mAb PD1.5 was prepared by immunizing IgH and IgK knock-out transgenic mice possessing a human immunoglobulin (heavy chain) minilocus with recombinant human PD-1-Fc protein consisting of the extracellular domain of PD-1 (amino acids 1-167) and the Fc portion of human IgG1, and Chinese hamster ovary (CHO) cells expressing human PD-1. Nivolumab was generated by grafting the variable regions of PD1.5 onto human kappa and IgG4 constant regions containing an S228P mutation (prevents Fab arm exchange with endogenous IgG4 antibodies). |
| Other Names | CD279; programmed death-1; programmed death 1, PD1; PD 1; Programmed cell death protein 1; hPD-1; hPD1; hPD 1; BMS-936558; MDX-1106;ONO-4538 |
| Gene, Accession # | UniProt: Q15116 |
| Catalog # | orb1821656 |
| Price | $618 |
| Order / More Info | PD-1 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
BIORBYT LTD.
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P: +44 (0)1223 859 353
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info@biorbyt.com
http://www.biorbyt.com
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Biorbyt LLC
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Email: info@biorbyt.com
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