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Antigenic Specificity | KDM2A |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | unconjugated |
Size | 100 ul |
Concentration | 1mg/ml |
Applications | ICC, IHC, IP, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. Required to sustain centromeric integrity and genomic stability, particularly during mitosis. |
Immunogen | A synthetic peptide of human FBXL11 |
Other Names | FBL7; CXXC8; FBL11; FBXL11; JHDM1A; LILINA |
Gene, Accession # | Gene ID: 22992, UniProt: Q9Y2K7 |
Catalog # | orb1731982 |
Price | $345 |
Order / More Info | KDM2A Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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