KDM2A Antibody from BIORBYT LTD.

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Antigenic SpecificityKDM2A
Clonemonoclonal
Host SpeciesRabbit
Reactive Specieshuman
IsotypeIgG
Formatunconjugated
Size100 ul
Concentration1mg/ml
ApplicationsICC, IHC, IP, WB
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DescriptionHistone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. Required to sustain centromeric integrity and genomic stability, particularly during mitosis.
ImmunogenA synthetic peptide of human FBXL11
Other NamesFBL7; CXXC8; FBL11; FBXL11; JHDM1A; LILINA
Gene, Accession #Gene ID: 22992, UniProt: Q9Y2K7
Catalog #orb1731982
Price$345
Order / More InfoKDM2A Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

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