Granzyme B Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-Granzyme B antibody, protein, ELISA kits.
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| Antigenic Specificity | Granzyme B |
| Clone | GZMB/3014 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b, kappa |
| Format | Protein G purified |
| Size | 100 ug, 20 ug |
| Concentration | n/a |
| Applications | IHC-P, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Granzyme B is a member of the granule serine protease family stored specifically in NK cells or cytotoxic T cells. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. Granzyme B is crucial for the rapid induction of target cell apoptosis by CTLs in the cell-mediated immune response. Granzyme B is useful as a marker in the identification of NK/T-cell lymphomas. High percentages of cytotoxic T-cells have been shown to be an unfavorable prognostic indicator in Hodgkin's Disease. |
| Immunogen | A recombinant human partial protein (amino acids 73-187) was used as the immunogen for the Granzyme B antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: P10144 |
| Catalog # | orb639875 |
| Price | $764 |
| Order / More Info | Granzyme B Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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