EpCAM Antibody from BIORBYT LTD.
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|---|---|
| Antigenic Specificity | EpCAM |
| Clone | Ber-EP4 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1, kappa |
| Format | supernatant |
| Size | 100 ul, 500 ul |
| Concentration | n/a |
| Applications | FACS, IHC-P |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes a 40-43kDa transmembrane epithelial glycoprotein, identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas with the exception of adult squamous epithelium, hepatocytes and gastric epithelial cells. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. It is also useful in distinguishing serous carcinomas of the ovary from mesothelioma. It has been reported that this epithelial antigen plays an important role as a tumor-cell marker in lymph nodes from patients with esophageal carcinoma otherwise classified as node-negative. Epithelial antigen has also been suggested as a discriminator between basal cell and baso-squamous carcinomas, and squamous cell carcinoma of the skin. |
| Immunogen | Human breast cancer MCF-7 cells were used as the immunogen for the EpCAM antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: P16422 |
| Catalog # | orb639791 |
| Price | $405 |
| Order / More Info | EpCAM Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
BIORBYT LTD.
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