LSD1 / Lysine-Specific Demethylase 1 Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-LSD1 / Lysine-Specific Demethylase 1 antibody, protein, ELISA kits.
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| Antigenic Specificity | LSD1 / Lysine-Specific Demethylase 1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | Protein A purified |
| Size | 100 ug, 25 ug |
| Concentration | n/a |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | LSD1 (Lysine-specific demethylase 1), also called KDM1 (lysine (K)-specific demethylase 1A), is the first histone demethylase to be identified and regulates transcription via demethylation of lysines 4 and 9 of Histone H3. It negatively regulates pro-inflammatory cytokine expression by interacting with the genes promoter region. It also plays a role in tumor development where overexpression of LSD1 correlates with a poor prognosis. It is upregulated in cancers of the bladder, breast, lung, colon, and GI tract as well as neuroblastoma and cells of mesenchymal origin such as chondrosarcoma, osteosarcoma, rhabdomyosarcoma and Ewing's sarcoma (Bennani-Baiti et al, 2012). |
| Immunogen | A recombinant protein fragment from the N-terminal region of human LSD1 was used as the immunogen for this antibody. |
| Other Names | n/a |
| Gene, Accession # | Gene ID: 23028 |
| Catalog # | orb248156 |
| Price | $643 |
| Order / More Info | LSD1 / Lysine-Specific Demethylase 1 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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