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Antigenic Specificity | PIAS1 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | mouse |
Isotype | n/a |
Format | caprylic acid-ammonium sulfate precipitate |
Size | 100 ul |
Concentration | n/a |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse monoclonal to PIAS1.PIAS1 is a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator oftranscription)] family of transcriptional modulators. PIAS1 functions as an E3 small ubiquitin-likemodifier (SUMO) ligase. It stabilizes the interaction between UBE2I and the substrate, and functionsas a SUMO-tethering factor. PIAS1 plays an important role in the transcriptional regulation ofnumerous cellular pathways, including STAT, NF-B, p53 and the steroid hormone signalingpathways. Recent studies revealed that PIAS1 is an important regulator for innate immunity,inflammatory cytokine signaling and regulatory T cell differentiation. |
Immunogen | C-terminal region of mouse PIAS1 |
Other Names | PIAS1,Protein inhibitor of activated STAT1,Pias1,DEAD,H boxbinding protein 1,Ddxbp1 |
Gene, Accession # | UniProt: O88907 |
Catalog # | orb66686 |
Price | $527 |
Order / More Info | PIAS1 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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