IDH2 Antibody from BIORBYT LTD.
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| Edit | |
|---|---|
| Antigenic Specificity | IDH2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 100 ul |
| Concentration | n/a |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit polyclonal to IDH2.Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate.These enzymes belong to two distinct subclasses, one utilizes NAD(+) as the electron acceptor andthe other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependentwhich localize to the mitochondrial matrix; and two NADP(+)-dependent, one of which is mitochondrialand the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. IDH2 isthe NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria, which plays a role inintermediary metabolism and energy production. IDH2 may tightly associate or interact with thepyruvate dehydrogenase complex. Defects in IDH2 are the cause of D-2-hydroxyglutaric aciduria type2 (D2HGA2), a neurometabolic disorder causing developmental delay, epilepsy, hypotonia, anddysmorphic features. |
| Immunogen | N-terminal region of human IDH2 |
| Other Names | IDH2,Isocitrate dehydrogenase [NADP] mitochondrial,IDH,ICDM,IDP,NADP(+)specific ICDH,Oxalosuccinate decarboxylase |
| Gene, Accession # | UniProt: P48735 |
| Catalog # | orb67195 |
| Price | $527 |
| Order / More Info | IDH2 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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